International Review of Ophthalmology ›› 2014, Vol. 38 ›› Issue (3): 156-159.doi: 10.3760/ cma. j. issn.1673-5803.2014.03.003
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ZHAO Ying-Xi, CHEN Xiang-Wu
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Abstract: Lyonization, also known as X chromosome inactivation, is a process that one of the two X chromosomes is inactivated in every somatic diploid cell during embryonic development in female mammals. Lyonization is involved in several X\|linked ocular diseases, such as choroideremia, X\|linked retinitis pigmentosa, and X\|linked ocular albinism. Insights of Lyonization may help in diagnosis and cure of ocular X\|linked recessive genetic diseases. (Int Rev Ophthalmol, 2014, 38: 156-159)
ZHAO Ying-Xi, CHEN Xiang-Wu. Lyonization and eye diseases[J]. International Review of Ophthalmology, 2014, 38(3): 156-159.
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URL: http://www.j-bio.net/EN/10.3760/ cma. j. issn.1673-5803.2014.03.003
http://www.j-bio.net/EN/Y2014/V38/I3/156